Journal of Applied Dental
and Medical Sciences
Journal of Applied Dental and Medical Sciences is A Quarterly Published

ABSTRACT

Evaluation of salivary interleukin levels in oral lichen planus patients

 Farheen Farooq,  Rahil Ahmad Bhatt

ABSTRACT

Background: This study aimed to assess the salivary levels of interleukin-8 (IL-8) in oral lichen planus (OLP) subjects. Material and methods: This descriptive cross-sectional study was conducted on 100 patients, out of which 80 had oral lichen planus while 20 subjects were chosen as controls. The salivary levels of IL-8 measured in all the subjects. Data was analyzed with one-way ANOVA and post hoc least significant difference tests. Results: The mean salivary level of IL-8 was higher among subjects with oral lichen planus than the control group. Conclusion: The increasing salivary level of IL-8 in OLP group indicates the role of this inflammatory cytokine in the pathogenesis of OLP.

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