Journal of Applied Dental
and Medical Sciences
Journal of Applied Dental and Medical Sciences is A Quarterly Published

ISSN : 2454-2288

Infobase Index Factor : 2.8

ABSTRACT

Acacia catechu and Acacia farnesiana as antimicrobial agents against periodontal pathogens: An in vitro assessment

Arati C. Koregol, Nagaraj B. Kalburgi , Ankita K. Kotecha

ABSTRACT

OBJECTIVES: To investigate the in vitro antimicrobial activity of different concentrations of ethanolic extracts of Acacia catechu and Acacia farnesiana (L.) against Aggregatibacter actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg).MATERIALS & METHODS: Antimicrobial activity of ethanolic extracts of Acacia catechu and Acacia farnesiana (L.) in various concentrations were analyzed for Aggregatibacter actinomycetemcomitans (Aa) and Porphyromonas gingivalis (Pg) by standard agar disc diffusion method. The Minimum Inhibitory Concentration (MIC) of these extracts was measured by Broth dilution method. Chlorhexidine was used as positive control. RESULTS: Acacia catechu showed profound antibacterial activity against Aggregatibacter actinomycetemcomitans (Aa) with the Zone of Inhibition of 25mm and against Porphyromonas gingivalis (Pg) with the zone of Inhibition of 18mm. Acacia catechu was inhibitory to Aa at all the serial dilutions ranging from 0.2?g/ml to 100?g/ml and to Pg at serial dilutions ranging from 12.5?g/ml to 100?g/ml. Acacia farnesiana showed intense antibacterial activity against Aggregatibacter actinomycetemcomitans (Aa) with the Zone of Inhibition of 18mm and against Porphyromonas gingivalis (Pg) with the zone of Inhibition of 20mm. Acacia farnesiana was inhibitory to Aa at all the serial dilutions ranging from 0.2?g/ml to 100?g/ml and to Pg at serial dilutions ranging from 12.5?g/ml to 100?g/ml. CONCLUSION: Acacia catechu & Acacia farnesiana may be used as an adjunct in treatment of periodontal diseases.

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