Dr. Amandeep, Dr. Aarti

ABSTRACT

Background: To assess the correlation between hyponatremia in hepatic encephalopathy of chronic liver disease. Materials & methods: A total of 50 patients were enrolled. All the patients were informed about the nature of the study and their verbal consent was obtained. After taking relevant history and physical examination, the venous blood sample of each patient was drawn. Mild to moderate encephalopathy was classified under grades I-II, while severe encephalopathy was classified under grades III-IV. Further evaluation was done accordingly and result was recorded. Results: Study included 34 (68%) males and 16 (32%) females. The mean age of the patients was 52.4 years. In patients with hyponatremia, it ranged from 113 to 129 meq/L. Hyponatremia was present in 18 (36%) subjects. 4 (8%) patients had mild hyponatremia, 9 (18%) had moderate, and 5 (10%) had severe hyponatremia. HE was present in 34 (68%) patients. HE grade I was present in 9 (18%), grade II in 11 (22%), grade III in 8(16%), and grade IV in 6 (12%) patients. Conclusion: There exists a correlation between the hyponatremia in hepatic encephalopathy of chronic liver disease.